Glyoxylic acid is a basic organic chemical raw material. Ethyl vanillin made from glyoxylic acid is widely used in perfumery and fixative, cosmetics and flavors. Allantoin made from glyoxylic acid. It can be used as a good healing agent for skin wounds, an additive for high-grade cosmetics and a plant growth regulator. In medicine, glyoxylic acid is used for the preparation of p-hydroxyphenylglycine (raw materials of hydroxyphenylpenicillin and cefalexin), p-hydroxyphenylacetamide (used as an effective agent for the treatment of cardiovascular diseases and hypertension - atel), and p-hydroxyphenylacetic acid, p-hydroxyphenylhydantoin and other pharmaceutical products.
Do you know how ethyl glyoxylate is synthesized?
Ethyl glyoxylate, as a derivative of glyoxylic acid, is an important intermediate in organic synthesis in the field of carbon and heterocyclic chemistry. Glyoxylic acid has played an important role in industrial production and practical application, and the research on ethyl glyoxylate has become more mature. However, it is difficult to synthesize glyoxylic acid directly by esterification because of the existence of aldehyde group. Owing to the great difference in the properties between ester groups in glyoxylate and carboxyl groups in glyoxylic acid, glyoxylate can replace glyoxylic acid in many organic synthesis reactions. Therefore, the synthesis of glyoxylate has attracted much attention. In fact, the synthesis of ethyl glyoxylate is relatively simple. Tartaric acid is used as raw material to produce ethyl glyoxylate directly by esterification reaction and oxidation of o-hydroxyl group in tartrate ester with oxidant, which breaks the carbon-carbon single bond.
How much do you know about the physical and chemical properties of ethyl glyoxylate
Physicochemical properties of ethyl glyoxylate and n-butyl glyoxylate Ethyl glyoxylate, also known as ethyl formyl formate. HCOCOOCH2CH3. Colorless transparent liquid, sensitive to air, sealed to avoid contact with air, may be part of the storage process in the form of polymerization, heating can be depolymerized. Its physical properties are as follows: boiling point 110 degrees Celsius, flash point 7 degrees C, density 1.03 g/mL at 20 degrees C.
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